IMPORTANT SAFETY INFORMATION AND INDICATION

Contraindications

EUCRISA is contraindicated in patients with known hypersensitivity to crisaborole or any component of the formulation.

Warnings and Precautions

Hypersensitivity reactions, including contact urticaria, have occurred in patients treated with EUCRISA and should be suspected in the event of severe pruritus, swelling and erythema at the application site or at a distant site. Discontinue EUCRISA immediately and initiate appropriate therapy if signs and symptoms of hypersensitivity occur.

Adverse Reactions

The most common adverse reaction occurring in ≥1% of subjects in clinical trials was application site pain, such as burning or stinging.

INDICATION

EUCRISA is indicated for topical treatment of mild-to-moderate atopic dermatitis in patients 2 years of age and older.

References: 1. EUCRISA® (crisaborole) Full Prescribing Information. October 2017. 2. Data on file. Pfizer Inc. New York, NY.

Please see Full Prescribing Information.

PP-CRI-USA-1085-01  © 2018 Pfizer Inc.

All rights reserved.         April 2018

For the treatment of mild-to-moderate atopic dermatitis in patients 2 and older

The specific mechanism(s) of action of
crisaborole in atopic dermatitis is not well defined. PDE4=phosphodiesterase 4.

EUCRISA is the
first and only steroid-free topical

PDE4 inhibitor.1

For topical use only. Not for ophthalmic, oral, or intravaginal use.

EUCRISA can be applied to the skin anywhere on the

face and body.1

Please see
IMPORTANT SAFETY INFORMATION and INDICATION below.

If signs and symptoms of hypersensitivity
occur, discontinue EUCRISA immediately and initiate appropriate therapy. EUCRISA was studied in pivotal trials for 29 days
and in an open-label safety extension study for up to 48 weeks.

EUCRISA can be used on all skin tones and has no limitations on

duration of use.1,2

Full Prescribing Information